1、成都中醫(yī)藥大學(xué)碩士學(xué)位論文針刺對(duì)持續(xù)性高眼壓大鼠視網(wǎng)膜神經(jīng)節(jié)細(xì)胞損害的干預(yù)研究姓名：黃珍珍申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：中醫(yī)五官科學(xué)（眼科學(xué)）指導(dǎo)教師：廖品正20060401成都中阪藥大學(xué)磺士學(xué)位瓴文ABSTRACTObjective：ToobservetheeffectofacBpunctureontheratmodelofchronic，moderatelyelevatedintraocularpressure(ioP)，andstudy

2、themechanismofitinitiallyMethods：Themodelofchronic，elevatedintraocularpressureratwasinducedbyAkriaTheratsweredividedinto3groupsrandomly：normalcontrolgroup，modelgroupandacupuncturetreatedgroupJingmingandTaichongpointsaret

3、hepointsofacupuncture，wereusedtotreattheratswithelevatedintraocularpressuretoobservetheeffectionOnmfERG，marphologieofretina。theapoptosisofretinalganglioncells(RGCs)bylabeleddextrampolymermethod(LDP)methodandmeasurethegan

4、glioneelllayerplyandnitricoxideinretinabynitratereductase《NO)method。Results：@Acupuncturecanpreventelevatingintraocularpressureeffectively。②Acupuncturecanimprovetheeyesightfunction：shorten那㈣P1wavetotalpeakfallowvolueandbu

5、iidupmfERGP1wavetotalfeedbackdensity。③AcupuncturecanrecedethethecontentofNOinretinaeffectively，consequentlyreduceitstoxicityeffecttoRGCs。④AcupuncturecanadjustandcontrolthegeneexpressioninRGCsofretina。Conclusion：aftercont

6、inuouselevatedintraocularpressureforlmonths。theexperimentaldiabeticratsshowedimmunohistochemJcatchangesofRGCs。Acupunctureo抽improvetheeyesightfunction。protectorli兩tentheapoptosisofRGCs。andpreventtheopticnervefromelevatedl